Spinach Artichoke Grilled Cheese

Bring one of your favorite appetizers to lunch or dinner with these Spinach and Artichoke Grilled Cheese Sandwiches. They are so cheesy and delicious!

Spinach Artichoke Grilled Cheese Sandwich on plate

Spinach Grilled Cheese

I think most can agree that you can’t go wrong with a Grilled Cheese Sandwich!! Although the kids are happy with the standard KRAFT cheese in the buttered bread, the hubby and I like to change it up a bit. Often times, we’ll make Paninis or just “fancy” grilled cheese sandwiches with avocados and cream cheese.

We recently tried a new version that has become a favorite. We made Spinach and Artichoke Grilled Cheese. I had tried Spinach and Artichoke Taquitos and had some left over mixture, and thought they’d be good in a sandwich. We were happy to give it a try and we loved the result.

The sandwiches were cheesy and tasted much like the Spinach and Artichoke Bread we posted awhile back We realize they may be a little more work than the regular grilled cheese, but they were so worth it!! In fact, I’m thinking these sandwiches would be good as appetizers too. Just cut them in four and add a toothpick, and these would be great at your next party.

Spinach artichoke mixture in bowl

How to Make Spinach and Artichoke Grilled Cheese

To make this yummy spinach grilled cheese sandwich, we recommend using Sourdough Bread. It makes for the best grilled cheese, although any bread works.

Begin by mixing sour cream, mayo, cream cheese, Parmesan cheese and minced garlic. Stir in spinach and artichoke hearts.

Butter bread and add a few tablespoons of mixture to the bread and grill on both sides until golden brown.

Spinach Grilled Cheese Sandwich on white plate

For more easy cheesy recipes, check out:

Spinach Artichoke Grilled Cheese Recipe

5 from 1 vote
Bring one of your favorite appetizers to lunch or dinner with these Spinach and Artichoke Grilled Cheese Sandwiches. They are so cheesy and delicious!
Course Main Course
Cuisine American
Prep Time 5 minutes
Cook Time 5 minutes
Total Time 10 minutes
Servings 4
Calories 718 kcal
Author Lil' Luna


  • 1/4 cup sour cream
  • 1/4 cup mayonnaise
  • 4 oz cream cheese softened
  • 1/2 cup grated parmesan cheese divided
  • 1/2 tsp minced garlic
  • 1/2 cup spinach frozen, thawed and drained
  • 4 oz artichoke hearts drained and chopped
  • 1/2 cup mozzarella cheese
  • butter
  • 8 slices sourdough bread


  • Mix sour cream, mayo, cream cheese, Parmesan cheese, and garlic until smooth. Stir in artichoke hearts and spinach.
  • Butter outside slices of bread and add a scoop of spinach/cheese mixture to bread. Spread around and fry on pan or griddle until both sides are golden brown.
  • Serve warm and ENJOY!

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About the Author

Kristyn Merkley

My name is Kristyn and I’m the mom of SIX stinkin’ cute kids and the wife to my smokin’ hot hubby, Lo. My mom’s maiden name is Luna, and I’m one of the many crafty “Lil’ Lunas” in the fam. On this site I like to share all things creative - from recipes to home decor to gifts and home decor ideas. Welcome!

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  1. Kristyn, why are there both jarred and frozen artichoke hearts in the recipe, or is it an either/or choice? I am looking forward to trying this.

    1. Oops, sorry!! You mix it in with the other ingredients in step 1 🙂 Sorry about that. I’ll have to fix it 🙂

  2. 5 stars
    Delicious! I ended up using brioche instead of sourdough, and that slight sweetness combined beautifully with the savory filling! My 21 month old is a fan, too, judging by the mess she’s made.