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If you’re looking for another way to enjoy chicken, look no further! With quick, easy prep and big flavor, this Mayo and Parmesan Chicken Bake is the answer to all your questions!

It’s one of our favorite baked chicken recipes. If you love simple chicken dinners, also check out our Creamy Swiss Chicken Bake and Bruschetta Chicken!

Mayo parmesan chicken on plate

delish mayo parm chicken

If you’ve seen all the chicken recipes on the site you’d know chicken is my meat of choice, but I just feel like there are so many things you can do with it and it’s always so good! You can bake it, fry it, shred it, use it in soups, add it to a casserole, or just enjoy it on its own!

This recipe is for a baked chicken, and it has the most flavorful, creamy mayo and parmesan mixture on top. I was surprised how tasty it was the first time I made it!

Prep time takes under 5 minutes and then you can throw it in the oven for a while (my favorite kind of recipe).

Chicken breast in baking dish

how to make mayo parmesan chicken

Simply place chicken breasts inside a greased 9×13 pan. Mix together the mayonnaise, Parmesan cheese, salt, pepper and garlic powder, and spread over the tops of each chicken breast. Sprinkle on more Parmesan cheese, if desired, and bake for 40-45 minutes. Easy peasy!

Low fat. The recipe calls for mayonnaise but for a healthier version I like to use non-fat vanilla or plain yogurt.

More crunch. You can also add a little more crunch by adding some bread crumbs or Panko on top along with the parmesan cheese.

TIP: Easy Clean up: Line your baking pan with foil and spray with nonstick spray or with parchment paper. 

Crock Pot Instructions

You can just as easily make this tasty mayo parmesan chicken in the slow cooker! Place the parmesan coated chicken in an oiled crockpot on high for 3-4 hours or on low for 6-8 hours.

Mayo parm chicken in baking dish

How to Store + Reheat

Refrigerate this Mayo Parmesan Chicken for up to 4 days. Any longer just store them in the freezer. Individually wrap chicken breasts in waxed paper or parchment. Place into freezer bags. Remove as much air as possible from bags seal, label and freeze for up to 4 months.

To reheat: Allow the chicken to thaw in the fridge for at least 8 hours, The chicken doesn’t need to be completely thawed, but must not be frozen solid. 

  • Preheat the oven to 225°F
  • Place the chicken pieces in a baking dish with a rack. Add ¼ -½ cup of water or chicken broth to the bottom. Place the breasts on top of the rack. You do not want the chicken to be sitting in the liquid. 
  • Add a tin foil tent to the top of the dish. This will help keep the chicken moist. Bake for 20-30 minutes or until the internal temperature reaches 165°F. (bake time will depend on how frozen the breasts still are and how hot your oven runs)

We like to pair this chicken with:

Mayo Parmesan chicken bake on dish

For more Baked Chicken recipes, check out:

5 from 127 votes

Mayo Parmesan Chicken Recipe

A delicious Parmesan Chicken Bake that is simple, yet full of flavor, and takes little prep time.
Servings: 6
Prep: 5 minutes
Cook: 40 minutes
Total: 45 minutes

Video

Ingredients 

  • 6 chicken breasts
  • 1 cup mayonnaise or 1 cup non-fat plain or vanilla yogurt
  • 1/3 cup parmesan cheese grated
  • 1 tsp salt
  • 1/2 tsp lemon pepper
  • 1/2 tsp garlic powder

Instructions 

  • Preheat oven to 350.
  • Place chicken breasts inside a greased 9×13 pan.
  • In a small bowl mix mayonnaise, Parmesan cheese, salt, pepper and garlic powder. Once well combined, spread over the tops of each chicken breast.
  • Sprinkle on more Parmesan cheese if desired and bake for 40-45 minutes.
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Nutrition

Calories: 534kcal, Protein: 50g, Fat: 35g, Saturated Fat: 6g, Cholesterol: 164mg, Sodium: 975mg, Potassium: 843mg, Vitamin A: 135IU, Vitamin C: 2.7mg, Calcium: 80mg, Iron: 1mg

Nutrition information is automatically calculated, so should only be used as an approximation.

About Kristyn

Kristyn Merkley is a published cookbook author, wife, mom of six, and major food enthusiast! For the past 15 years, she has been sharing foolproof, family-friendly recipes—each one tested in her kitchen—that anyone can master. As a seasoned recipe creator, she loves making cooking simple, stress-free, and totally doable for everyone!

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5 from 127 votes (102 ratings without comment)

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Recipe Rating




65 Comments

  1. Cynthia says:

    5 stars
    This was yummy. I added some sliced pepperocinos & a little of the juice and it was to live for.

  2. Patty says:

    5 stars
    I loved this recipe for how moist and flavorful the chicken came out, but I also loved the ease in preparing this chicken dish. I am physically disabled so I am so happy to have this recipe to add to my simple yet delicious meals to look forward to. One question: What is the best way to reheat it without drying out the leftover chicken?

  3. Fanny Koeswanto says:

    What to do with the lemon pepper?

    1. Lil'Luna Team says:

      You will add it in with the rest of the spices.

  4. tim says:

    covered or not?

    1. Lil'Luna Team says:

      Not covered

  5. Sharon Ferguson says:

    Do you use boneless/ skinless chicken or bone in skin . Thanks

    1. Lil'Luna Team says:

      I liked to use boneless, skinless, but really it can be whatever you like 🙂

  6. Lauren says:

    5 stars
    Came out fantastic! I was practically licking the pan from the leftover browned topping extras. My fiancé loved it, too. We’ll definitely be making this again, thanks!

  7. LVC says:

    5 stars
    Absolutely delicious and so easy to make. This is top on my list of favorites!!

  8. Renee Lowe says:

    This was so easy and delicious!

  9. Linda Stentzel says:

    5 stars
    My daughter made this while I was visiting. All of us loved it. She is married with 4 children. I will make this myself at home.

    1. Lil'Luna Team says:

      I’m so happy to hear you enjoyed the chicken!! Thanks for sharing!

  10. Terry McAllister says:

    So easy and so delicious! Will definitely be one on my favourite list. Can’t wait to serve this to company.. great with brown rice and any veg. Slurp!

    1. Lil'Luna Team says:

      I’m so happy to hear you enjoyed the recipe!! Thanks for sharing.

  11. Debbie says:

    5 stars
    Just absolutely awesome!

    1. Lil'Luna Team says:

      Glad you think so 😉 Thank you!!

  12. Amy Austin says:

    5 stars
    It’s delicious!!!!

    1. Lil'Luna Team says:

      Oh I’m so glad to hear you enjoyed the recipe!

  13. Amanda says:

    5 stars
    I can’t believe I waited so long to try this. So quick. So delicious. It will be in my dinner rotation now. My daughter is not a big meat eater – it’s an eternal fight, especially now that she is so active in sports. She actually ate a whole piece of chicken tonight without a fight!

    1. Lil'Luna Team says:

      Hooray!! It’s always a win when the kids enjoy the meal too. So glad you found the recipe!

  14. George Money says:

    I love the chicken breast mayo sour cream recipe. It’s very tender and moist.. I have shared this recipe many times.

    1. Lil'Luna Team says:

      Thank you!! So glad to hear you enjoy the recipe!

  15. pam says:

    Yummy!🤪

    1. Lil'Luna Team says:

      Thank you!! So glad you enjoyed it!

  16. Louise says:

    5 stars
    Easy, but incredibly delicious!!

    1. Lil'Luna Team says:

      Yay!! That’s what we are all about. Easy and tasty! So glad you enjoyed the recipe.

  17. Leesa says:

    5 stars
    Great recipe, I sprinkled with Italian bread crumbs before baking.

    I used minced garlic instead of garlic powder.

    I went without lemon pepper because I didn’t have any.

    Turned out flavorful, and juicy. A new keeper for me!

    1. LilLunaTeam says:

      I’m so glad you enjoyed the recipe! Thanks for sharing what you do. I’m so happy it’s now a “keeper” for you!

  18. Imelda says:

    5 stars
    This is easy and very moist and tasty

    1. Lil'Luna Team says:

      Thank you! I love it when recipes can be easy and yummy!

  19. Sharon Drahos says:

    5 stars
    Love this chicken. Before the put this in the oven I sprinkle it with bread crumbs. It’s also very good this way

    1. Lil'Luna Team says:

      Oh that does sound yummy! Thanks for sharing!

  20. Melissa Mathew says:

    5 stars
    Easy recipe and also delicious. Very similar to the Swiss chicken bake.

    1. LilLunaTeam says:

      Thanks so much for trying it! I love easy and delicious and I’m so glad you felt the same about this chicken bake recipe!

  21. Lisa Lacy says:

    5 stars
    My whole family loves this recipe! It’s on an almost weekly repeat at our house. Even my Mayo hating boys love it. The chicken is so tender and juicy. Definitely a family favorite ♥️

  22. Stephanie says:

    5 stars
    The mayo seems like a weird ingredient but it’s not at all!! It keeps the chicken so moist and gives it a delicious flavor. Yum! Yum! Yum!

  23. Marisela says:

    5 stars
    I love your recipes

    1. Kristyn Merkley says:

      Awe, thank you!! I am glad you do 🙂

  24. Linda says:

    DO we know the carbs and sugar? I didnt see it in the nutritional inFO.

    1. Kristyn Merkley says:

      I do not, but you can find an online converter that you put the ingredients in & it will tell you 🙂

  25. Kristina says:

    5 stars
    the lemon pepper really adds brightness to the dish. Yum!

  26. Natalie says:

    5 stars
    Oh, my, this chicken is so good!! It’s so simple & & the ingredients go so well together!

  27. Amy L Huntley says:

    5 stars
    I am always on the look out for new chicken recipes. I tried this with the non-Fat yogurt and it was so delicious. The chicken was tender and had amazing flavor!

  28. Joy says:

    5 stars
    yum! We love making this! My kids love it, too! It’s a family favorite!

  29. Olivia says:

    5 stars
    This chicken dish is a favorite. So eaSy and delicious!

  30. Melissa Budahn says:

    5 stars
    Made this a couple TIMEs. First time as written. Second time i crumbled Ritz crackers on top. I will make it with ritz crackers from here on out. So good and very most.

  31. Scott says:

    Did you bake it covered or uncovered?

    1. Kristyn Merkley says:

      Uncovered 🙂

  32. michele says:

    what kind of parmesan cheese is used? shredded/grated?

    1. Lil' Luna says:

      I used grated 🙂 Enjoy!

  33. pat says:

    Love your recipes…looking forward to trying most of them…..thanks in Alabama

  34. cindy says:

    5 stars
    My daughter and I love this. We have mace it with the mayo once and yogurt the other. Obviously the mayo was a little tastier but the yogurt was good too. Also, I think next time I will omit the salt. The cheese is already so salty.

    1. Lil' Luna says:

      I’m glad you like this!! And omitting the salt is a good idea if it’s already salty. 😉 Thanks for stopping by!

      1. Lorna says:

        Is the mayonnaise chicken to be covered whilst in oven. So frustrating when it doesn’t say

      2. Kristyn Merkley says:

        No, it does not. I only add that, if it needs to be covered.

  35. christine says:

    Wish i knew what temp to cook chicken.. Made it tonight and guessed….

    1. taylor says:

      What temp did you use?

      1. Lil' Luna says:

        Sorry – it is 350. 😉

    2. Lil' Luna says:

      It’s 350. What temp did you end up using and did you like it?

  36. Brittney says:

    What temperature are you supposed to cook the chicken on?

  37. Courtnee says:

    This looks so yummy!!! What temperature do you put the oven on?

  38. Phoebe @ Feed Me Phoebe says:

    The use of non-fat yogurt instead of mayo is brilliant! Love how simple this recipe is. xo

  39. Christina says:

    My kind of recipe, quick and easy. Chicken is our meat of choice here too. Thanks!

  40. Gina says:

    Oh good heavens – I have had this before & it’s really delish. I should know better than to click over before lunch 🙂 Now I really want this.