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Cheesy Chicken Alfredo Bake is a simple twist on a family favorite! It’s an easy dinner, perfect any night of the week.

A twist on a classic Chicken Alfredo, this chicken alfredo casserole is just as cheesy and delicious. Serve it with soup or salad for a complete meal!

A close up of chicken alfredo casserole being scooped from a baking dish.
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casserole version of a classic

Who doesn’t love Pasta?! We make at least one pasta dish a week.

Our favorites include Spaghetti, Homemade Mac and Cheese, Creamy Penne Pasta – you name it!

We LOVE Fettuccine Alfredo and knew a casserole version with chicken would be just as good. We were right… this recipe is a family favorite and is on the monthly rotation because it’s loved by all.

Penne pasta for Chicken Alfredo casserole recipe.

How to Make

OPTIONAL MARINADE. If time allows, marinate the chicken. Add chicken and Italian dressing to a bag. Let sit overnight or even a few hours to make the chicken tender and full of flavor.

PASTA. Cook pasta as directed. Drain and set aside.

While pasta is cooking, heat 1-2 TB of oil in a skillet on medium heat.

CHICKEN. Slice your marinated chicken in half so they are thinner pieces. This will help them cook through evenly.

  • In a bowl, mix salt, pepper, thyme, and poultry seasoning. Rub it on all sides of your chicken breasts.
  • Add chicken to hot oil and cook on both sides until done (about 15-20 minutes).
  • Remove to a plate to let cool.
Wooden spoon filled with alfredo sauce over a saucepan of alfredo sauce.

Continued…

SAUCE. While the chicken is cooling, preheat your oven to 350°F and start on your sauce. In a separate large skillet melt the butter; add garlic and cook for 1-2 minutes.

  • Using a wire whisk, mix in flour and stir until bubbly.
  • Mix in half & half and milk (you can also sub these two for heavy cream), and stir to combine. Bring to a boil and then reduce to low heat and simmer for 5 minutes.
  • With your whisk, mix in 1½ cups of cheese. Cook an additional 5 minutes until the sauce starts to thicken.
  • Remove sauce from heat.

ASSEMBLE. Cut your cooked chicken into bite-size pieces and add to a large bowl. Add the pasta to your bowl and then the sauce. Mix everything to combine.

BAKE. Spray a 9×13 baking dish with nonstick spray. Add the pasta mixture to the pan and sprinkle with an additional 1½ cups of cheese.

Sprinkle with pepper and bake for 30 minutes or until bubbly and golden brown. Garnish the dish with chopped parsley, if desired.

A white mixing bowl full of shredded chicken.

Recipe Tips

Pasta. Alfredo sauce is often served over fettuccine noodles, but we chose to use penne noodles for this baked dish. Other pasta choices include mini penne or rigatoni.

Veggies. Add broccoli, spinach, peas, corn, bell peppers, or mushrooms.

Chicken. Use leftover chicken or rotisserie chicken to save time. Make chicken alfredo pasta bake without chicken or substitute the chicken with cooked sausage. Mix in shrimp or add crumbled bacon on top. 

Kraft 5 Italian Cheese Blend contains mozzarella cheese, provolone cheese, parmesan cheese, asiago cheese, and romano cheese. Shred your own cheese blend using these cheeses.

Baked chicken Alfredo casserole in a baking dish ready for cooking.

What to serve with Baked Chicken Alfredo

There are so many sides and bread that go great with this chicken alfredo casserole. Here are some of our favorites:

Storing Info

Make ahead of time. Prepare as directed, cover, and place in the fridge. We typically do this the night before or the morning of, but it can be stored up to 24 hours before baking.

STORE leftovers in an airtight container(s) in the fridge for 3-4 days.

FREEZE. Allow the ingredients to cool and then wrap the dish with plastic wrap and again with aluminum foil. If done properly, it will keep for up to 2-3 months in the freezer.

Reheat. The best way to reheat a large amount is in the oven or on the stovetop. Reheat slowly over low heat and add extra milk to help smooth out the texture.

If you are in a hurry, or on the go, reheat smaller portions in the microwave. 

Scooping chicken alfredo bake from a baking dish.

Recipe FAQ

What is the difference between chicken alfredo and chicken fettuccine?

Chicken alfredo is made with a creamy white sauce, whereas chicken fettuccine can be made with any kind of sauce.

What goes best with chicken alfredo casserole?

We love to serve this casserole with Garlic Knots, Roasted Vegetables, or any one of our green salads!

Do I have to use penne pasta for this recipe?

Nope! You can use any type of pasta that pairs well with rich and creamy sauces. Linguine or rigatoni would be great in this dish!

For more cheesy pasta recipes, check out:

4.97 from 104 votes

Chicken Alfredo Bake Recipe

By: Lil’ Luna
Cheesy Chicken Alfredo Casserole is a simple twist on a family favorite! It's an easy dinner, perfect any night of the week.
Servings: 8 people
Prep: 35 minutes
Cook: 30 minutes
Total: 1 hour 5 minutes

Ingredients 

  • 12 oz. pkg penne pasta
  • 3 boneless skinless chicken breasts marinated in Italian dressing if desired
  • vegetable oil
  • 1/4 tsp thyme
  • 1/4 tsp poultry seasoning
  • salt and pepper to taste
  • 2 TB olive oil
  • 1/2 c butter
  • 2 tsp minced garlic
  • 4 TB all-purpose flour
  • 3 c half and half
  • 3 c milk
  • 3 c Kraft Italian Five Cheese Blend divided
  • Italian Seasoning, garnish

Instructions 

  • If time allows, always try to marinate your chicken. Throw them in a bag of Italian dressing and let sit overnight or even a few hours will help your chicken to be tender and full of flavor.
  • Cook pasta as directed. Drain and set aside.
  • While pasta is cooking, heat 1 – 2 TB of oil in a skillet on medium heat.
  • Slice your marinated chicken in half so they are thinner pieces. This will help them cook through evenly.
  • In a bowl mix salt, pepper, thyme and poultry seasoning and rub it on all sides of your chicken breasts. Add chicken to hot oil and cook on both sides until done (about 15-20 minutes). Remove to a plate to let cool.
  • While the chicken is cooling, preheat your oven to 350°F and start on your sauce. In a separate large skillet melt the butter; add garlic and cook for 1 – 2 minutes.
  • Using a wire whisk, mix in flour and stir until bubbly. Mix in half & half and milk, stir to combine. Bring to a boil and then reduce to low heat and simmer for 5 minutes.
  • With your whisk, mix in 1½ cup of cheese. Cook an additional 5 minutes until sauce starts to thicken. Remove sauce from heat.
  • Cut your cooked chicken into bite size pieces and add to a large bowl. Add the pasta to your bowl and then the sauce. Mix everything to combine.
  • Spray a 9×13 baking pan with non stick spray. Add the pasta mixture to the pan and sprinkle with an additional 1½ cup of cheese.
  • Sprinkle with pepper and bake for 30 minutes or until bubbly and golden brown.

Video

Nutrition

Calories: 588kcal, Carbohydrates: 11g, Protein: 34g, Fat: 44g, Saturated Fat: 25g, Cholesterol: 171mg, Sodium: 539mg, Potassium: 593mg, Sugar: 5g, Vitamin A: 1275IU, Vitamin C: 2.1mg, Calcium: 513mg, Iron: 0.9mg

Nutrition information is automatically calculated, so should only be used as an approximation.

About Kristyn

My name is Kristyn and I’m the mom of SIX stinkin’ cute kids and the wife to my smokin’ hot hubby, Lo. My mom’s maiden name is Luna, and I’m one of the many crafty “Lil’ Lunas” in the fam. On this site I like to share all things creative - from recipes to home decor to gifts and home decor ideas. Welcome!

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4.97 from 104 votes (72 ratings without comment)

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Recipe Rating




150 Comments

  1. Brent says:

    5 stars
    This came out wonderfull but used 2 cups les on the milk/ 1/2&1/2. Added broccoli and it was great. thanks for sharing!

    1. Kristyn Merkley says:

      Glad to share!! Thank you for trying it!

    2. Pam says:

      So what was the total amount of milk and total amount of half and half you used?

  2. Amber says:

    5 stars
    My kids beg for this! So good

  3. Ashley Bird says:

    5 stars
    One of my very favorite pastas to make! So delicious! And easy! We have this one a month!

  4. Beverly says:

    5 stars
    Just subscribed to this website recently. LOve the RECIPES! I prep my dinner for the week every sunday. I have used at least one of your recipes every week. Very delicious and easy. Instructions included on make ahead or Freeze. Thank you and keep the recipes coming.

    1. Kristyn Merkley says:

      You are so welcome & I am so glad to hear that! Thank you!

  5. KatiE says:

    Any kind Of italian dressing?

    1. Kristyn Merkley says:

      Yep, any kind of Italian dressing 😉 Enjoy!

  6. Deanna says:

    5 stars
    So good! i recommend using fennel in the chicken marinade or when you’re cooking it. Cheers.

    1. Kristyn Merkley says:

      Glad you liked it! Thank you so much!

  7. Jill Morgan says:

    3 stars
    This was OK BUT THERE WAS NO “ALFREDO” TASTE TO IT. I LOVE YOUR WEBSITE AND USE A LOT OF YOUR RECIPES BUT THIS I PROBABLY WOULDN’T MAKE AGAIN…SORRY

    1. Kristyn Merkley says:

      No worries..thank you for trying it 🙂

  8. Cassidy Howard says:

    Can you use heavy whipping cream instead of the half and half? If so how mUch should i use?

    1. Kristyn Merkley says:

      I personally have not tried that, so I would need to experiment on the right amount of half & half. I wouldn’t want to tell you the wrong amount.

  9. Ann says:

    In stead of making the sauce can i use jared Alfredo sauce???

    1. Kristyn Merkley says:

      Yes, of course 🙂 Enjoy!!

  10. Meredith says:

    I know, it probably doesn’t taste as good, but could you use a jar of alfredo sauce & wood you recommend adding anything to it if I did that to doctor it up some??

    1. Kristyn Merkley says:

      You sure could. I would just continue to add the spices on the recipe 🙂 Hope you like it!