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Simple turkey tetrazzini is a flavorful pasta casserole, perfect for using leftover holiday turkey, but tasty year round!

A spoonful of Turkey Tetrazzini up close.
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best way to use leftover turkey!

We love to gather with the Luna gang at Thanksgiving and fill our bellies with all the classics! Even with a crowd, we inevitably have leftovers (probably because we all love food, and bring way too much!)

One item we always have leftovers of is Turkey, and although we love turkey sandwiches, our go-to main dish to make with leftovers is turkey tetrazzini. It’s easy, cheesy and delicious and is the perfect variation of our class Chicken Tetrazzini.

WHY WE LOVE IT:

  • It’s delicious! With butter, sour cream, cheese, pasta and more, this recipe is hard NOT to love.
  • Simple. This recipe is so easy. Mix, combine, and dump for an easy dinner idea.
  • Loved by all. Turkey on its own isn’t always the whole family’s favorite, but add tetrazzini and it’s a hit with everyone.
Soup, cheese, sour cream and other ingredients on a counter.

Ingredients

  • 16 ounces linguine – switch the linguine noodles for cooked spaghetti noodles, or egg noodles. Boil 16 ounces of noodles in a large pot of salted water for added flavor.
  • 3 cups cooked turkey – this is a perfect dish for leftover turkey, but you can purchase fully cooked turkey or buy thick slices of turkey from the deli and chop it at home.
  • ½ cup butter use salted or unsalted butter
  • 2 (10.5-ounce) cans cream of celery soup – or cream of chicken or cream of mushroom soup
  • 2 cups sour cream – adds a creamy tangy flavor as well as thickens the sauce
  • 1 teaspoon garlic salt (with parsley flakes)
  • ½ teaspoon black pepper
  • 1 cup chicken broth chicken stock or vegetable broth can also be used
  • 2 tablespoons grated Parmesan cheese 
  • 2 cups shredded Mozzarella cheese 
  • ¼ cup Italian bread crumbs (optional) – or top with Panko breadcrumbs for a crunchy topping and fresh parsley for color

How to make Turkey Tetrazzini

  1. PREP. Preheat oven to 350°F. Grease a 9×13-inch baking dish and set aside.
  2. PASTA. Cook 16 ounces linguine according to package directions. Drain and set aside.
  3. SAUCE. Meanwhile, in a large bowl, combine 3 cups chopped turkey, ½ cup butter, 2 (10.5-ounce) cans cream of celery soup, 2 cups sour cream, 1 teaspoon garlic salt, ½ teaspoon pepper, and 1 cup chicken broth in a medium bowl. Stir in noodles until well combined.
  4. BAKE. Pour into prepared baking dish. Sprinkle 2 tablespoons grated Parmesan cheese and 2 cups shredded Mozzarella cheese on top and ¼ cup Italian bread crumbs (if desired).
    • Bake for 36–42 minutes, until cheeses are melted and bubbling.

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4.99 from 407 votes

Turkey Tetrazzini

By: Lil’ Luna
Simple turkey tetrazzini is a flavorful pasta casserole, perfect for using leftover holiday turkey, but tasty year round!
Servings: 8
Prep: 10 minutes
Cook: 35 minutes
Total: 45 minutes

Ingredients 

  • 16 ounces linguine, cooked
  • 3 cups chopped cooked turkey
  • ½ cup butter, softened
  • 2 (10.5-ounce) cans cream of celery, (or cream of chicken)
  • 2 cups sour cream
  • 1 teaspoon garlic salt (with parsley flakes)
  • ½ teaspoon pepper
  • 1 cup chicken broth
  • 2 tablespoon grated Parmesan cheese
  • 2 cups shredded Mozzarella cheese
  • ¼ cup Italian bread crumbs, (optional)

Instructions 

  • Preheat oven to 350°F. Grease a 9×13 baking dish and set aside.
  • Cook linguine according to package directions. Drain and set aside.
  • Meanwhile, in a large bowl, combine chopped turkey, butter, cream of celery soup, sour cream, garlic salt, pepper, and chicken broth in a medium bowl. Stir in noodles until well combined.
  • Pour into prepared baking dish. Sprinkle grated Parmesan cheese and shredded Mozzarella cheese on top and Italian bread crumbs (if desired).
  • Bake for 36–42 minutes, until cheeses are melted and bubbling.

Video

Notes

STORE leftover turkey tetrazzini in an airtight container in the fridge for about 3 days.
Freeze the entire casserole. Cool completely and cover it with heavy-duty foil. Freeze for up to 4 months. For a freezer meal, cook noodles al dente.
  • Thaw in the fridge for 24 hours before baking it. Bake, uncovered, at 350° for 35 minutes or so, until the edges are bubbling and it’s heated through.
  • Bake it from frozen. Leave it covered with tinfoil and add an extra 45 minutes or so to the bake time. Uncover for the last 15 minutes of baking.

Nutrition

Calories: 240kcal, Carbohydrates: 3g, Protein: 6g, Fat: 22g, Saturated Fat: 13g, Cholesterol: 63mg, Sodium: 672mg, Potassium: 80mg, Sugar: 1g, Vitamin A: 685IU, Vitamin C: 1.8mg, Calcium: 162mg, Iron: 0.3mg

Nutrition information is automatically calculated, so should only be used as an approximation.

What are some variations?

> Mushrooms. Add sautéed mushrooms before stirring in the noodles.
> Peas. Add frozen peas when you combine the noodles and sauce mixture.
> Onions. Add diced onions to the mixture or green onions on top.
> Add some heat. For more spicy flavor to the dish by sprinkling on red pepper flakes or hot sauce.

How to store turkey tetrazzini?

Leftover turkey tetrazzini casserole in an airtight container in the refrigerator for about 3 days.
Reheat. The easiest way to reheat the leftovers is in the microwave. It can be reheated on the stovetop, over medium heat, or in the oven.

How to Freeze?

Divide leftovers into individual portions and freeze them for 1-2 months. Add milk or heavy cream when reheating to not be gritty.

About Kristyn

My name is Kristyn and I’m the mom of SIX stinkin’ cute kids and the wife to my smokin’ hot hubby, Lo. My mom’s maiden name is Luna, and I’m one of the many crafty “Lil’ Lunas” in the fam. On this site I like to share all things creative - from recipes to home decor to gifts and home decor ideas. Welcome!

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4.99 from 407 votes (337 ratings without comment)

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115 Comments

  1. Jessica says:

    Can you use ground turkey? I don’t have any sliceable breast on hand since we are outside the holiday seasons. If so, how much should you use?

    1. Lil'Luna Team says:

      You could try using ground turkey! The recipe calls for 3 cups of cooked turkey, so you could use about the same. I’d say about 1.5 lbs of raw ground turkey. You’ll have to let us know how you enjoy it with the ground turkey.

  2. None Biz says:

    5 stars
    Simple, but I would use less liquid next time.

    1. Kismet says:

      5 stars
      I always make this with cooked chicked and I saute onions, red, yellow, orange peppers and garlic in butter and add it for color. So delicious.

  3. Angel says:

    5 stars
    Really yummy, used cream of chicken with herbs and cream of celery, added mushrooms. Subbed penne, perfect for leftover turkey when you’re really tired of eating tùrkey.